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Invitrogen™ DEFB132 Polyclonal Antibody

Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 32, also known as beta-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.
Specifications
Specifications
| Antigen | DEFB132 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | DEFB132 |
| Gene Accession No. | Q7Z7B7 |
| Gene Alias | BD-32; Beta-defensin 132; beta-defensin 32; DEFB132; DEFB32; DEFB-32; defensin beta 132; defensin HEL-75; Defensin, beta 132; defensin, beta 32; HEL-75; KFLL827; RP5-1103G7.6; UNQ827; UNQ827/PRO1754 |
| Gene Symbols | DEFB132 |
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