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Invitrogen™ DEPDC5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA563150
This item is not returnable.
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Description
Immunogen sequence: YDAQVFRLPG PSRAQCLTTC RSVRERESHS RKSASSCDVS SSPSLPSRTL PTEEVRSQAS DDSSLGKSAN ILMIPHPHLH QYEVSSS Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.
This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants.
Specifications
| DEPDC5 | |
| Polyclonal | |
| Unconjugated | |
| DEPDC5 | |
| DEP domain containing 5; DEP domain-containing protein 5; DEP.5; DEPD5; DEPDC5; FFEVF; GATOR complex protein DEPDC5; KIAA0645 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9681 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O75140 | |
| DEPDC5 | |
| Recombinant protein corresponding to Human DEPDC5. Recombinant protein control fragment (Product #RP-95351). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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