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  6. Invitrogen™ Desmin Recombinant Rabbit Monoclonal Antibody (23GB3120), Invitrogen™

Invitrogen™ Desmin Recombinant Rabbit Monoclonal Antibody (23GB3120), Invitrogen™
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Product Code. p-200087674
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Product Code. Quantity unitSize
30087615 100 μL 100µL
30089911 20 μL 20µL
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Product Code. 30087615 Supplier Invitrogen™ Supplier No. MA553598

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Description

Rabbit Recombinant Monoclonal Antibody

Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.
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Specifications

Antigen Desmin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB3120
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DES
Gene Accession No. P17661, P48675
Gene Alias CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Gene Symbols DES
Host Species Rabbit
Immunogen A synthesized peptide derived from human Desmin (410-470AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1674, 64362
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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