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Invitrogen™ Desmocollin 2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582465
This item is not returnable.
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Description
Immunogen sequence: KTVIICKPTM SSAEIVAVDP DEPIHGPPFD FSLESSTSEV QRMWRLKAIN DTAARLSYQN DPPFGSYVVP ITVRDRLGMS SVTSLDVTLC DCITENDCTH RVDPRIGGGG VQLGKW Highest antigen sequence indentity to the following orthologs: Rat - 70%, Mouse - 74%.
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Specifications
| Desmocollin 2 | |
| Polyclonal | |
| Unconjugated | |
| DSC2 | |
| ARVC10; ARVD10; ARVD11; AW228162; Cadherin family member 2; CDHF2; CDHF5; CDHF6; CMD1BB; desmocollin 2; desmocollin-2; Desmocollin-3; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DSC2; Dsc2a; Dsc2b; DSC3; Epithelial type 2 desmocollin; HDGC; PVA | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1824 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q02487 | |
| DSC2 | |
| Recombinant protein corresponding to Human DSC2. Recombinant protein control fragment (Product #RP-90654). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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