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Invitrogen™ Desmocollin 3 Polyclonal Antibody
Sheep Polyclonal Antibody
Brand: Invitrogen™ PA547909
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Description
In direct ELISAs, approximately 25% cross-reactivity with recombinant human Desmocollin-3 is observed, and approximately 5% cross-reactivity with recombinant mouse (rm) Desmocollin-1 and rmDesmocollin-2 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Specifications
| Desmocollin 3 | |
| Polyclonal | |
| Unconjugated | |
| Dsc3 | |
| 5430426I24Rik; ARVC10; ARVD10; Cadherin family member 3; CDHF3; CDHF5; CDHF6; CMD1BB; desmocollin 3; desmocollin-3; Desmocollin-4; desmoglein-2; desmoglein-3; DSC; DSC1; DSC2; DSC3; DSC4; HDGC; HT-CP; PVA | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 13507 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Immunohistochemistry (Frozen), Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P55850 | |
| Dsc3 | |
| Mouse myeloma cell line NS0-derived recombinant mouse Desmocollin-3 Arg136-Leu695. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
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