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Dexamethasone, 96%, Thermo Scientific™

Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.

Brand:  Thermo Scientific Acros 230302500

Additional Details : CAS : 50-02-2 Weight : 0.05025kg


Packaging Glass bottle
Quantity 250mg

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Product Code. 10053130

  • € 50.54 / 250mg

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Description

Description

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Information

• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways

Applications

• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

Specifications

Chemical Identifiers

50-02-2
392.47
UREBDLICKHMUKA-CXSFZGCWSA-N
5743
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
C22H29FO5
MFCD00064136
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
CHEBI:41879
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

Specifications

Dexamethasone
White
0.5% max. (105°C, 3 hrs)
Authentic
MFCD00064136
15, 2945
250mg
UREBDLICKHMUKA-CXSFZGCWSA-N
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
392.47
95% min. (on dried substance)
392.46
96%
50-02-2
255.0°C to 261.0°C
96%
C22H29FO5
Glass bottle
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
+ 75.00
5743
CHEBI:41879
Crystalline Powder
(HPLC) Passes test
Videos
Safety and Handling

Safety and Handling

Product Identifier
  • Dexamethasone

Signal Word
  • Warning

Hazard Category
  • Carcinogenicity Category 2

Hazard Statement
  • H351-Suspected of causing cancer.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

SDS Documents
Certificates
Special Offers

Special Offers

RUO – Research Use Only