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Invitrogen™ DIAPH1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA596420
Description
Immunogen sequence: TEEKMRRAKL AKEKAEKERL EKQQKREQLI DMNAEGDETG VMDSLLEALQ SGAAFRRKRG PRQANRKAGC AVTSLLASEL TKDDAMAAVP AKVSKNSETF PTILEEAKEL VGRAS; Positive Samples: HL-60, MCF7, 293T, HepG2, Mouse liver, Mouse lung; Cellular Location: Cell membrane, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane.
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Specifications
| DIAPH1 | |
| Polyclonal | |
| Unconjugated | |
| DIAPH1 | |
| D18Wsu154e; DFNA1; DIA1; Diap1; Diaph1; diaphanous 1; diaphanous homolog 1; diaphanous homolog 1 (Drosophila); diaphanous related formin 1; diaphanous-1; diaphanous-related formin 1; Diaphanous-related formin-1; DRF1; FLJ25265; hDIA1; LFHL1; mDIA1; p140DIA; p140mDia; Protein diaphanous homolog 1; SCBMS | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 13367, 1729 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot, Immunocytochemistry | |
| 0.66 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O08808, O60610 | |
| DIAPH1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1149-1263 of human DIAPH1 (NP_0010732801). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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