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  8. Difluoromethyl phenyl sulfone, 95%

Difluoromethyl phenyl sulfone, 95%

Codice prodotto. 15432099
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250 mg
1 g
5 g
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1g
250mg
5g
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Codice prodotto. 15432099 Fornitore Thermo Scientific Alfa Aesar N. del fornitore H64760.06
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Estimated Shipment: 12-10-2026
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Descrizione

CAS: 1535-65-5 | C7H6F2O2S | 192.18 g/mol

Used as a reagent for the nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls and fluorination. Reagent used for reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors, difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation. Also used as reagent in preparation of α-difluoromethyl amines via stereo selective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines and Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used as a reagent for the nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls and fluorination. Reagent used for reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors, difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation. Also used as reagent in preparation of α-difluoromethyl amines via stereo selective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines and Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes.

Solubility
Soluble in chloroform and water.

Notes
Keep container tightly closed. With adequate ventilation. Store away from oxidizing agent.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 1535-65-5
Molecular Formula C7H6F2O2S
Molecular Weight (g/mol) 192.18
MDL Number MFCD01050170
InChI Key LRHDNAVPELLXDL-UHFFFAOYSA-N
Synonym difluoromethyl sulfonyl benzene, difluoromethyl phenyl sulfone, difluoromethanesulfonylbenzene, phenyl difluoromethyl sulfone, benzene, difluoromethyl sulfonyl, difluoromethyl sulfonylbenzene, difluoro-methanesulfonyl-benzene, difluoromethyl sulfonyl-benzene
PubChem CID 11816356
IUPAC Name difluoromethylsulfonylbenzene
SMILES C1=CC=C(C=C1)S(=O)(=O)C(F)F

Specifica

Melting Point 24°C to 25°C
Density 1.324
Refractive Index 1.5
Quantity 5 g
Beilstein 2259218
Solubility Information Soluble in chloroform and water.
Formula Weight 192.18
Percent Purity 95%
Chemical Name or Material Difluoromethyl phenyl sulfone

RUO – Research Use Only

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