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Invitrogen™ DKK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA590096

Product Code. 16567681

  • € 520.00 / 100µL

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Description

Description

Immunogen sequence: CMVCRRKKKR CHRDGMCCPS TRCNNGICIP VTESILTPHI PALDGTRHRD RNHGHYSNHD LGWQNLGRPH TKMSHIKGHE GDPCLRSSDC IEGFCCARHF WTKICKPVLH QGEVCTKQRK KGSHGLEIFQ RCDCAKGLSC KVWKDATYSS KARLHVCQKI; Positive Samples: A-549, NCI-H460.

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DKK2
Polyclonal
Unconjugated
DKK2
dickkopf 2; dickkopf 2 homolog; Dickkopf gene 2; dickkopf homolog 1; dickkopf homolog 2; dickkopf homolog 2 (Xenopus laevis); dickkopf homolog 4; dickkopf related protein-2; dickkopf WNT signaling pathway inhibitor 2; dickkopf-2; Dickkopf-related protein 2; DKK2; DKK-2; Dkk4; hDkk-2; mDkk-2; UNQ682/PRO1316
Rabbit
Affinity chromatography
RUO
27123
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
2.84 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Q9UBU2
DKK2
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human DKK2 (NP_0552361).
100 μL
Primary
Human
Antibody
IgG
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