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Invitrogen™ DLL3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA526336
This item is not returnable.
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Description
DLL3 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.
Specifications
| DLL3 | |
| Polyclonal | |
| Unconjugated | |
| Dll3 | |
| delta like canonical Notch ligand 3; Delta3; delta-like 3; delta-like 3 (Drosophila); delta-like protein 3; Dll3; Drosophila Delta homolog 3; M-Delta-3; pu; pudgy; SCDO1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10683, 114125, 13389 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.48 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| O88516, O88671, Q9NYJ7 | |
| Dll3 | |
| KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human DLL3. | |
| 200 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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