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Invitrogen™ DLL4 Recombinant Rabbit Monoclonal Antibody (003), HRP
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Product Code. 30019360
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Quantity:
100 μg
Unit Size:
100µg
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30019360 100 μg 100µg
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Product Code. 30019360 Supplier Invitrogen™ Supplier No. MA552153

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Description

Rabbit Recombinant Monoclonal Antibody

DLL4 Recombinant Monoclonal Antibody for ELISA

Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DLL4
Applications ELISA
Classification Recombinant Monoclonal
Clone 003
Concentration 100 μg/mL
Conjugate HRP
Formulation PBS with no preservative
Gene Dll4
Gene Accession No. Q9NR61
Gene Alias AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341
Gene Symbols Dll4
Host Species Rabbit
Immunogen Recombinant Human DLL4 protein (Ser 27-Pro524).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54567
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Product Type Antibody
Form Liquid
Isotype IgG
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