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Invitrogen™ DMGDH Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA557660
This item is not returnable.
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Description
Immunogen sequence: TLATDDVDPE GNESIWYNGK VVGNTTSGSY SYSIQKSLAF AYVPVQLSEV GQQVEVELLG KNYPAVIIQE PLVLTEPTRN RLQK Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Specifications
| DMGDH | |
| Polyclonal | |
| Unconjugated | |
| DMGDH | |
| 1200014D15Rik; AI787269; dimethylglycine dehydrogenase; dimethylglycine dehydrogenase precursor; dimethylglycine dehydrogenase, mitochondrial; Dmgdh; DMGDHD; EC 1.5.99.2; M2GD; ME2GLYDH | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 29958 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9UI17 | |
| DMGDH | |
| Recombinant protein corresponding to Human DMGDH. Recombinant protein control fragment (Product #RP-96850). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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