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DMOG, MedChemExpress

Product Code. 16481786
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Product Code. 16481786 Supplier Medchem Express Supplier No. HY15893

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Description

MedChemExpress DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.

Specifications

Chemical Name or Material DMOG
CAS 89464-63-1
Color White
Purity Grade Notes Research
Molecular Formula C6H9NO5
Quantity 500 mg
Synonym Dimethyloxallyl Glycine
Solubility Information DMSO : ≥ 50 mg/mL (285.49 mM) ∣H2O : 50 mg/mL (285.49 mM; Need ultrasonic)
SMILES O=C(OC)CNC(C(OC)=O)=O
Molecular Weight (g/mol) 175.14
Formula Weight 175.14
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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