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Description
Antibody detects endogenous levels of total DNase II.
DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
Specifications
Specifications
| Antigen | DNase II |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide |
| Gene | DNASE2 |
| Gene Accession No. | O00115, Q9QZK8 |
| Gene Alias | acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; DNASE2; Dnase2a; DNL; Dnl2; lysosomal DNase II; R31240_2 |
| Gene Symbols | DNASE2 |
| Show More |
Product Title
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