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Invitrogen™ DOK7 Polyclonal Antibody

Description
Antibody detects endogenous levels of total DOK7.
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | DOK7 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | DOK7 |
| Gene Accession No. | Q18PE0, Q18PE1 |
| Gene Alias | A930013K19Rik; AW049091; C4orf25; CMS10; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; EF-12; Oit5; oncoprotein induced transcript 5; protein Dok-7; RGD1566416 |
| Gene Symbols | DOK7 |
| Show More |
Product Title
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