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Invitrogen™ Doublecortin Polyclonal Antibody
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Product Code. 15648038
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Quantity:
100 μL
Unit Size:
100µL
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15648038 100 μL 100µL
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Product Code. 15648038 Supplier Invitrogen™ Supplier No. PA517428

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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Doublecortin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 165 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene DCX
Gene Accession No. O43602, O88809, Q9ESI7
Gene Alias DBCN; Dbct; DC; Dcn; DCX; doublecortex; doublecortin; doublin; lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Gene Symbols DCX
Host Species Rabbit
Immunogen Synthetic peptide corresponding to human doublecortin.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13193, 1641, 84394
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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