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Invitrogen™ DPH5 Polyclonal Antibody

Product Code. 16331945
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Quantity:
100 μL
Unit Size:
100µL
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16331945 100 μL 100µL
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Product Code. 16331945 Supplier Invitrogen™ Supplier No. PA584994

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLRATKLGIP YRVIHNASIM NAVGCCGLQL YKFGETVSIV FWTDTWRPES FFDKVKKNRQ NGMHTLCLLD IKVKEQSLEN LIKGRKIYEP PRYMS Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 94%.

This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
TRUSTED_SUSTAINABILITY

Specifications

Antigen DPH5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DPH5
Gene Accession No. Q9H2P9
Gene Alias AD-018; CGI-30; diphthamide biosynthesis 5; diphthamide biosynthesis methyltransferase; Diphthine methyl ester synthase; diphthine synthase; DPH5; DPH5 homolog; HSPC143; NPD015; protein x 0011
Gene Symbols DPH5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DPH5. Recombinant protein control fragment (Product #RP-108077).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51611
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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