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Invitrogen™ DPH5 Polyclonal Antibody
Beskrivelse
Immunogen sequence: VLRATKLGIP YRVIHNASIM NAVGCCGLQL YKFGETVSIV FWTDTWRPES FFDKVKKNRQ NGMHTLCLLD IKVKEQSLEN LIKGRKIYEP PRYMS Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 94%.
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Tekniske data
Tekniske data
| Antigen | DPH5 |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | DPH5 |
| Gene Accession No. | Q9H2P9 |
| Gene Alias | AD-018; CGI-30; diphthamide biosynthesis 5; diphthamide biosynthesis methyltransferase; Diphthine methyl ester synthase; diphthine synthase; DPH5; DPH5 homolog; HSPC143; NPD015; protein x 0011 |
| Gene Symbols | DPH5 |
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Produkttitel
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