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Invitrogen™ DPPA2 Polyclonal Antibody
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Product Code. 15694145
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Quantity:
100 μL
Unit Size:
100µL
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15694145 100 μL 100µL
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Product Code. 15694145 Supplier Invitrogen™ Supplier No. PA550218

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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total DPPA2 protein.

The DPPA2 (Developmental Pluripotency Associated 2) gene is prominently expressed in embryonic stem cells and is critical for maintaining their pluripotency and self-renewal capabilities. Located on chromosome 3, DPPA2 belongs to a family of genes that play significant roles in early embryonic development and epigenetic remodeling. The expression of DPPA2 is tightly regulated through mechanisms such as DNA methylation, and it is involved in regulatory pathways that control the expression of core pluripotency factors. Beyond its role in stem cell biology, DPPA2 expression is also noted in various cancers, where it can become reactivated, suggesting its involvement in oncogenic processes. In the context of cancer, DPPA2, along with DPPA4, has been studied for its potential to facilitate cellular reprogramming and contribute to tumorigenesis. Given its expression pattern, DPPA2 serves as both a marker of pluripotent potential in stem cells and a potential target for cancer diagnostics and therapy due to its reactivation in malignant tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DPPA2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene DPPA2
Gene Accession No. Q7Z7J5
Gene Alias 2410088E07Rik; C80932; cancer/testis antigen 100; CT100; D19Mgi18; developmental pluripotency associated 2; developmental pluripotency-associated 2; developmental pluripotency-associated protein 2; DPPA2; ECAT15-2; ECSA; embryonic stem cell (ESC) associated transcript 15-2; embryonic stem cell-associated transcript 15-2 protein; LOC683282; PESCRG1; Phsecrg1; Pluripotent embryonic stem cell-related gene 1 protein; similar to developmental pluripotency-associated 2
Gene Symbols DPPA2
Host Species Rabbit
Immunogen Fusion protein corresponding to a region derived from internal residues of human developmental pluripotency associated 2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151871
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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