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Description
Immunogen sequence: SCTGTLVVHL DDYNDHAPQI DKEVTICQNN EDFAVLKPVD PDGPENGPPF QFFLDNSASK NWNIEEKDGK TAILRQRQNL DYNYYSVPIQ IKDRHGLVAT HMLTVRVCDC STPSECRMKD KSTR Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 70%.
The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.
Specifications
Specifications
| Antigen | DSC1 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | DSC1 |
| Gene Accession No. | Q08554 |
| Gene Alias | 1110020A10Rik; AI507491; Cadherin family member 1; CDHF1; desmocollin 1; Desmocollin1; desmocollin-1; Desmosomal glycoprotein 2/3; DG2/DG3; DSC1; Dsc1a; Dsc1b |
| Gene Symbols | DSC1 |
| Show More |
Product Title
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