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Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.
Brand: Thermo Scientific™ A39267
Additional Details : CAS : 68528-80-3 Weight : 0.05200kg
Description
Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.
- Reactive groups: NHS ester (both ends)
- Reactive towards: amino groups (primary amines)
- Amine reactive sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
- Membrane-permeable, allowing for intracellular crosslinking
- High purity, crystalline reagent can be used to create high-purity conjugates
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO); compare to BS3 (Sulfo-DSS)
Specifications
| Amine-Amine | |
| DSS | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| NHS Ester | |
| Solid | |
| DMF, DMSO | |
| No |
| No | |
| 368.35 | |
| 11.4 Å | |
| Yes | |
| No-Weigh™ | |
| Homobifunctional | |
| Medium (10 to 30 Å) | |
| 10 x 2 mg | |
| Standard, Single-use | |
| Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.