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Invitrogen™ DTX3L Monoclonal Antibody (K24022_12C6), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA555814

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Product Code. 30197900

  • € 438.00 / 50µg

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This item is not returnable. View return policy

Description

Description

Sequence of this protein is as follows: RVRRKLESYF QSSKSSGGGE CTVSTQEHEA PGTFRVEFSE RAAKERVLKK GEHQILVDEK PVPIFLVPTE NSIKKNTRPQ ISSLTQSQAE TPSGDMHQHE

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DTX3L
Monoclonal
1 mg/mL
PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Q8TDB6
DTX3L
Recombinant human DTX3L (immunogen range is 21-120).
50 μL
Primary
Human
Antibody
IgG1
Western Blot
K24022_12C6
Unconjugated
DTX3L
AU042200; Bbap; BC023741; B-lymphoma- and BAL-associated protein; deltex 3 like, E3 ubiquitin ligase; deltex 3-like; deltex 3-like (Drosophila); deltex E3 ubiquitin ligase 3L; DTX3L; E3 ubiquitin-protein ligase DTX3L; Protein deltex-3-like; RGD1565144; rhysin 2; Rhysin2; rhysin-2; RING-type E3 ubiquitin transferase DTX3L
Mouse
Protein A
RUO
151636
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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