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Invitrogen™ DTYMK Recombinant Rabbit Monoclonal Antibody (23GB5235), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA553870
This item is not returnable.
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Description
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
Specifications
| DTYMK | |
| Recombinant Monoclonal | |
| Unconjugated | |
| DTYMK | |
| AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 1841 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB5235 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P23919 | |
| DTYMK | |
| A synthesized peptide derived from human DTYMK (160-200AA). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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