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Invitrogen™ PACAP Receptor Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA3115
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Description
PA3-115 detects PAC1 in human samples. PA3-115 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40-60 kDa protein representing PAC1 in human samples. In immunohistochemistry, PAC1 immunoreactivity is predominantly localized to the plasma membrane. PA3-115 immunogen is a synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human VPAC2 receptor.
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
Specifications
| PACAP Receptor | |
| Polyclonal | |
| Unconjugated | |
| ADCYAP1R1 | |
| 2900024I10Rik; ADCYAP receptor type I; ADCYAP1 R1; ADCYAP1R 1; Adcyap1r1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; adenylate cyclase activating polypeptide 1 receptor 1; adenylate cyclase activating polypeptide 1 type 1 receptor; AI846590; alternatively spliced product of PACAP receptor; G-protein coupled receptor; PAC 1; PAC1; PAC1 receptor; Pac1 receptors; PAC1R; PAC1-R; PACAP R 1; PACAP Receptor; PACAP receptor 1; PACAP type I receptor; PACAP type IA receptor; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; PACAP1-R; PACAPR; PACAPR1; PACAP-R1; PACAP-R-1; PACAPR1A; PACAP-R1A; PACAP-R-1A; PACAPRI; pituitary adenylate cyclase activating polypeptide 1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; pituitary adenylate cyclase activating polypeptide receptor; pituitary adenylate cyclase-activating polypeptide type 1 receptor; pituitary adenylate cyclase-activating polypeptide type 1 receptor hop 1 splice variant; pituitary adenylate cyclase-activating polypeptide type I receptor; pituitary adenylate cyclase-activating polypeptide type IA receptor; pvr1 | |
| Rabbit | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Conc. Not Determined | |
| whole serum with 0.05% sodium azide | |
| P41586, P70205 | |
| ADCYAP1R1 | |
| Synthetic peptide, KLH conjugated, corresponding to the residues L (450) S K S S S Q I R M S G L P A D N L A T(468) of human PAC1. | |
| RUO | |
| 11517, 117 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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