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E 2012, MedChemExpress

Product Code. 16472808
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16472808 10 mg 10mg
16415557 5 mg 5mg
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Product Code. 16472808 Supplier Medchem Express Supplier No. HY10016

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Description

MedChemExpress E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.

E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.

Specifications

Chemical Name or Material E 2012
CAS 870843-42-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C25H26FN3O2
Quantity 10 mg
Solubility Information DMSO : ≥ 50 mg/mL (119.19 mM)
SMILES O=C(N([C@H](C1=CC=C(C=C1)F)C)CCC/2)C2=C\C3=CC=C(N4C=NC(C)=C4)C(OC)=C3
Molecular Weight (g/mol) 419.49
Formula Weight 419.49
Percent Purity 97.39%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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