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Tocris Bioscience™ E 2012
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Product Code. 18768726
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18768726 10 mg 10mg
18777096 50 mg 50mg
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Product Code. 18768726 Supplier Tocris Bioscience™ Supplier No. 5550/10

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Description

γ-secretase modulator; Notch-sparing

E 2012 is a γ-secretase modulator. Lowers Aβ40 and Aβ42 levels and increases Aβ37 levels, in vitro and in vivo. Displays no effect on γ-secretase processing of Notch, EphA4 and EphB2.
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Specifications

Chemical Name or Material (3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone
CAS 870843-42-8
Quantity 10 mg
Molecular Formula C25H26FN3O2
Formula Weight 419.49
Purity 98%
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