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Gibco™ Mouse IL-12 p80 Recombinant Protein, PeproTech®

Product Code. 30088085
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Quantity:
10 x 50 μg
2 x 50 μg
5 x 50 μg
Unit Size:
Pack of 10
Pack of 2
Pack of 5
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Product Code. 30088085

Brand: Gibco™ 21012P80H500

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Description

Recombinant Protein

IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicates that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or it can form the homodimer designated IL-12 p80. Elevated levels of IL-12 p80 correlate to macrophage recruitment and increased inflammation in asthma and respiratory viral infection models.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P43432
For Use With (Application) Functional Assay
Formulation Protein with no preservative
Gene ID (Entrez) 16160
Molecular Weight (g/mol) 80 kDa
Name IL-12 p80
Quantity 10 x 50 μg
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias IL-12; Interleukin
Gene Symbol IL12B
Conjugate Unconjugated
Recombinant Recombinant
Activity Determined by its ability to inhibit the proliferative effect of 2 ng/ml mIL-12 p70 in T cell-enriched PBMCs.
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade ≥95% by SDS-PAGE gel and HPLC analyses.
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