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Invitrogen™ EDEM1 Polyclonal Antibody
Description
Positive Control: Jurkat, Jurkat membrane extract Predicted Reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (100%), Bovine (92%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Specifications
Specifications
| Antigen | EDEM1 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1.21 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | EDEM1 |
| Gene Accession No. | Q92611 |
| Gene Alias | A130059K23Rik; EDEM; EDEM1; ER degradation enhancer, mannosidase alpha-like 1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1; KIAA0212; mKIAA0212; RGD1563633 |
| Gene Symbols | EDEM1 |
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