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Invitrogen™ EEF1E1 Polyclonal Antibody
Description
Immunogen sequence: MAAAAELSLL EKSLGLSKGN KYSAQGERQI PVLQTNNGPS LTGLTTIAAH LVKQANKEYL LGSTAEEKAI VQQWLEYRVT QVDGHSSKND IHTLLKDLNS; Positive Samples: 293T, HeLa, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Nucleus.
This gene encodes a multifunctional protein that localizes both in the cytoplasm and in the nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage and plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | EEF1E1 |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1.36 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | EEF1E1 |
| Gene Accession No. | O43324, Q9D1M4 |
| Gene Alias | 1110003A02Rik; AIMP3; Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; ARS-interacting multifunctional protein 3; Eef1e1; Elongation factor p18; eukaryotic translation elongation factor 1 epsilon 1; eukaryotic translation elongation factor 1 epsilon-1; Multisynthase complex auxiliary component p18; multisynthetase complex auxiliary component p18; P18; p18 component of aminoacyl-tRNA synthetase complex |
| Gene Symbols | EEF1E1 |
| Show More |
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