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Invitrogen™ EFHA1 Polyclonal Antibody

Description
EFHA1 Polyclonal Antibody for Western Blot
Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.
Specifications
Specifications
| Antigen | EFHA1 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 2% sucrose and 0.09% sodium azide |
| Gene | MICU2 |
| Gene Accession No. | Q8IYU8 |
| Gene Alias | 09C01; 1110008L20Rik; 4833427E09Rik; AU041871; Calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; EFHA1; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; Micu2; mitochondrial calcium uptake 2; RGD1309934; Smhs2; Smhs2 homolog |
| Gene Symbols | MICU2 |
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