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Invitrogen™ EFHC2 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA556951

Product Code. 15744851

  • € 566.00 / 100µL

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Description

Description

Immunogen sequence: KEKFHKSQHW GFCNNVMMLV SDEKPGIGGE PLLGQKIKPK CSIYPKGDGS DVPSWVAFDK QVLSFDAYLE EEVLDKSQTN YRIR Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.

EFHC2 (EF-hand domain-containing protein 2) is a gene located on the X chromosome at position Xp11.4. The protein encoded by EFHC2 is characterized by the presence of EF-hand motifs, which are helix-loop-helix structural domains capable of binding calcium ions. The EFHC2 protein is involved in various cellular processes, particularly those that are calcium-dependent, such as signal transduction and regulation of enzyme activities. EFHC2 has been implicated in neurological functions and conditions. For instance, it has been studied in the context of epilepsy, where variants in the gene are associated with increased susceptibility to juvenile myoclonic epilepsy. Additionally, EFHC2 is expressed in the brain and testis, suggesting roles in neurodevelopment and reproduction.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

EFHC2
Polyclonal
Unconjugated
EFHC2
4933407D04Rik; dJ1158H2.1; EF-hand domain (C-terminal) containing 2; EF-hand domain containing 2; EF-hand domain-containing family member C2; Efhc2; mental retardation, X-linked 74; mRib72-2; MRX74
Rabbit
Antigen affinity chromatography
RUO
74405, 80258
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.6 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q5JST6, Q9D485
EFHC2
Recombinant protein corresponding to Human EFHC2. Recombinant protein control fragment (Product #RP-95475).
100 μL
Primary
Human, Mouse
Antibody
IgG
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