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EGFR Antibody (DH8.3), Alexa Fluor™ 750 - Mutant, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-50599AF750

Product Code. 18134878

  • € 555.00 / 0.10mL

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Description

Description

EGFR Monoclonal specifically detects EGFR in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

EGFR
Monoclonal
Alexa Fluor 750
50 mM sodium borate with 0.05% sodium azide
EGFR
Synthetic peptide corresponding to the junctional region of the truncated receptor LEEKKGNYVVTDHC,conjugated to keyhole limpet haemcyanin.
Primary
Clone DH8.3 of EGF R/ErbB1 antibody is specific for Truncated EGFR which is also called EGFR type III, EGFRvIII or delta-EGFR (characterized by a deletion of 267 amino acids in the extracellular domain, leading to a receptor which is unable to bind ligand yet is constitutively active). Because of its impaired internalisation and degradation, EGFRvIII is known to enhance tumourigenesis. NOTE: Clone DH8.3 DOES NOT cross-react with full length or wildtype EGFR (wtEGFR).
Store at 4°C in the dark.
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry
DH8.3
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Mouse
0.1 mL
1956
Human
IgG1
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