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EID1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. p-7204099 Shop All Proteintech Products
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Quantity:
20 μL
150 μL
Unit Size:
150µL
20µL
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Product Code. Quantity unitSize
16839013 20 μL 20µL
16829013 150 μL 150µL
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Product Code. 16839013 Supplier Proteintech Supplier No. 117341AP20UL

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Description

Rabbit Polyclonal Antibody

E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.

Specifications

Antigen EID1
Applications Western Blot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EID1
Gene Accession No. Q9DCR4, Q9Y6B2
Gene Alias 21 kDa pRb associated protein, C15orf3, CRI1, EID 1, EID1, IRO45620, PNAS 22, PTD014, RBP21
Gene Symbols Eid1
Host Species Rabbit
Immunogen EID1 Fusion Protein Ag2336
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23741, 58521
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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