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Invitrogen™ EIF2S1 Polyclonal Antibody

Description
Recommended positive controls: A549, H1299, HCT-116, rat neuron, HeLa, N2a. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (92%), Chicken (97%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
Specifications
Specifications
| Antigen | EIF2S1 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.63 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | EIF2S1 |
| Gene Accession No. | P05198, P68101, Q6ZWX6 |
| Gene Alias | 0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01 |
| Gene Symbols | EIF2S1 |
| Show More |
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