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Invitrogen™ EIF2S1 Recombinant Rabbit Monoclonal Antibody (PSH04-29)

Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA552465
Description
Positive Control: MCF7 cell lysate, HepG2 cell lysate, HeLa cell lysate, COS-1 cell lysate, A549 cell lysate, RAW264.7 cell lysate, C6 cell lysate, mouse kidney tissue lysate, mouse spleen tissue lysate, rat kidney tissue lysate, rat spleen tissue lysate, HepG2, human breast tissue, mouse breast tissue, rat breast tissue. Sequence Similarities: 99% Mouse/Rat. Subcellular Location: Cytoplasm, Stress granule. Predicted band size: 36 kDa.
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
Specifications
| EIF2S1 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.1 BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| P05198, P68101, Q6ZWX6 | |
| EIF2S1 | |
| Recombinant protein within human eif2s1 aa 1-315/315. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Monkey | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| PSH04-29 | |
| Unconjugated | |
| EIF2S1 | |
| 0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 13665, 1965, 54318 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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