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Invitrogen™ eIF3i Polyclonal Antibody
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Product Code. 13491707
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Quantity:
100 μL
Unit Size:
100µL
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13491707 100 μL 100µL
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Product Code. 13491707 Supplier Invitrogen™ Supplier No. PA527582

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, H1299, HeLa, HepG2. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (88%), Pig (98%), Rabbit (96%), Chicken (92%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF3i
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Eif3i
Gene Accession No. Q13347
Gene Alias 36kDa; D4Ertd632e; eIF3 p36; eIF-3-beta; eIF3-beta; Eif3i; eIF3-p36; Eif3s2; Eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; PRO2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP1; TRIP-1
Gene Symbols Eif3i
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human EIF3 beta. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8668
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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