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Invitrogen™ eIF4G3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA589943
This item is not returnable.
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Description
Immunogen sequence: HKEAKIEEQE EQRKVQQLMT KEKRRPGVQR VDEGGWNTVQ GAKNSRVLDP SKFLKITKPT IDEKIQLVPK AQLGSWGKGS SGGAKASETD ALRSSASSLN RFSALQPPAP SGSTPSTPVE FDSRRTLTSR GSMGREKNDK PLPSATARPN TFMRGGSSKD LLDNQSQEEQ RREMLETVKQ LTGGVDVERN STEAERNKTR E; Positive Samples: LO2, HeLa.
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
Specifications
| eIF4G3 | |
| Polyclonal | |
| Unconjugated | |
| EIF4G3 | |
| 1500002J22Rik; 4833436O05; 4930523M17Rik; eIF4G 3; eIF-4G 3; Eif4g3; eIF-4-gamma 3; eIF-4-gamma II; eIF4GII; eukaryotic translation initiation factor 4 gamma 3; eukaryotic translation initiation factor 4 gamma, 3; G1-419-52; repro8; RP11-190H11.1 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 8672 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 0.74 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| O43432 | |
| EIF4G3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human EIF4G3 (NP_0037512). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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