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Invitrogen™ eIF5A Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102548

Product Code. 16689014

  • € 493.00 / 100µL

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Description

Description

Antibody detects endogenous levels of total EIF5A1.

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

eIF5A
Polyclonal
Unconjugated
EIF5A
AA410058; D19Wsu54e; Eif4d; eIF-4D; Eif5a; eIF-5A; EIF5A1; eIF-5A1; eIF-5A-1; eIF5AI; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; MGC104255; MGC99547; OTTHUMP00000128384; Rev-binding factor; uORF A
Rabbit
Affinity chromatography
RUO
1984, 276770, 287444
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P63241, P63242, Q3T1J1
EIF5A
A synthesized peptide derived from human EIF5A(Accession P63241), corresponding to amino acid residues G97-V147.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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