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Invitrogen™ Embigin Polyclonal Antibody
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Product Code. 16566251
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Quantity:
100 μL
Unit Size:
100µL
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16566251 100 μL 100µL
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Product Code. 16566251 Supplier Invitrogen™ Supplier No. PA587887

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGSAPDSPFT SPPLREEIMA NNFSLESHNI SLTEHSSMPV EKNITLERPS NVNLTCQFTT SGDLNAVNVT WKKDGEQLEN NYLVSATGST LYTQYRFTII NSKQMGSYSC FFREEKEQRG TFNFKVPELH GKNKPLISYV GDSTVLTCKC QNCFPLNWTW YSSNGSVKVP VGVQMNKYVI NGTYANETKL KITQLLEEDG ESYWCRALFQ LGESEEHIEL VVLSYLVP; Positive Samples: Jurkat, MCF-7, THP-1; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, synapse.

Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis. A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion. Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Embigin
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EMB
Gene Accession No. Q6PCB8
Gene Alias AL022799; EMB; Embigin; embigin homolog; glycoprotein 70; Gp70; Teratocarcinoma glycoprotein Gp-70
Gene Symbols EMB
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_9408511).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133418
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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