missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Emerin Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5114452
This item is not returnable.
View return policy
Description
Positive controls that may be used include: Human Skeletal Muscle Tissue Lysate.
Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight. The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar ultraviolet (UV)-induced DNA damages. Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA. The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region. A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity. A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity. Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.
Specifications
| Emerin | |
| Polyclonal | |
| Unconjugated | |
| Emd | |
| AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 13726, 2010, 25437 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| O08579, P50402, Q63190 | |
| Emd | |
| Emerin antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Emerin. The immunogen is located within the first 50 amino acids of Emerin. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction