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Invitrogen™ ENSA Polyclonal Antibody
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Product Code. 16331015
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100 μL
Unit Size:
100µL
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16331015 100 μL 100µL
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Product Code. 16331015 Supplier Invitrogen™ Supplier No. PA584060

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Rabbit Polyclonal Antibody

Immunogen sequence: MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAK Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ENSA
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ENSA
Gene Accession No. O43768
Gene Alias 1700020C18Rik; 2610007F17Rik; AI451924; Alpha-endosulfine; ARPP-19e; endosulfine alpha; endosulfine-alpha variant 1; endosulfine-alpha variant 3; ENSA
Gene Symbols ENSA
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ENSA. Recombinant protein control fragment (Product #RP-101350).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2029
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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