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Tocris Bioscience™ Entacapone
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Product Code. 30001572
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001572

Brand: Tocris Bioscience™ 4720/50

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This item is not returnable. View return policy

Description

Potent COMT inhibitor; blocks α-synuclein aggregation

Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits α-synuclein aggregation in an in vitro assay; blocks α-synuclein-induced cell death in PC-12 cells.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 130929-57-6
Molecular Formula C14H15N3O5

Specifications

Quantity 50 mg
Formula Weight 305.29
Purity >99%
Molecular Weight (g/mol) 305.29
Chemical Name or Material Entacapone
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