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Invitrogen™ EPC1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA576826
This item is not returnable.
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Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Specifications
| EPC1 | |
| Polyclonal | |
| Unconjugated | |
| EPC1 | |
| 2400007E14Rik; 5730566F07Rik; A930032N02Rik; DKFZp781P2312; enhancer of polycomb 1; enhancer of polycomb homolog 1; enhancer of polycomb homolog 1 (Drosophila); Epc1; Epl 1; Epl1; mir-1893 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 13831, 80314 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8C9X6, Q9H2F5 | |
| EPC1 | |
| Recombinant full length Human EPC1. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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