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Invitrogen™ Epstein Barr Virus GP350 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA581825
This item is not returnable.
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Description
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350.
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
Specifications
| Epstein Barr Virus GP350 | |
| Polyclonal | |
| Unconjugated | |
| EBV gp350 | |
| Recombinant Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein. | |
| 100 μL | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA | |
| 1 mg/mL | |
| PBS with no preservative | |
| Rabbit | |
| Protein A | |
| RUO | |
| Virus | |
| Antibody | |
| IgG |
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