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Invitrogen™ ERCC1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585347

Product Code. 16362285

  • € 520.00 / 100µL

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Description

Description

Keep as concentrated solution. Predicted reactivity: Mouse (94%), Rat (93%), Pig (95%), Chimpanzee (100%), Bovine (96%). Positive Control: HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ERCC1
Polyclonal
Unconjugated
ERCC1
COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511
Rabbit
Antigen affinity chromatography
RUO
2067
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.86 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P07992
ERCC1
Recombinant protein encompassing a sequence within the center region of human ERCC1. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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