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  6. Invitrogen™ ERCC1 Recombinant Rabbit Monoclonal Antibody (23GB1230), Invitrogen™

Invitrogen™ ERCC1 Recombinant Rabbit Monoclonal Antibody (23GB1230), Invitrogen™
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Product Code. 30089022
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30089022 100 μL 100µL
30087715 20 μL 20µL
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Product Code. 30089022 Supplier Invitrogen™ Supplier No. MA554188

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Description

Rabbit Recombinant Monoclonal Antibody

ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERCC1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB1230
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ERCC1
Gene Accession No. P07903, P07992
Gene Alias COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511
Gene Symbols ERCC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ERCC1 (1-180AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13870, 2067
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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