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ESRRB Monoclonal Antibody (OTI1E6), TrueMAB™, OriGene

Product Code. 17555393
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100 μL
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30µL
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17555393 100 μL 100µL
17575393 30 μL 30µL
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Product Code. 17555393 Supplier Origene Technologies Supplier No. TA805455

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Description

Mouse Monoclonal Antibody

ESRRB (steroid hormone receptor ERR2) plays a role in maintaice of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells. ESSRB also regulates expression of multiple rod-specific genes and is required for survial of this cell type. Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35).

Specifications

Antigen ESRRB
Applications Western Blot
Classification Monoclonal
Clone OTI1E6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ESRRB
Gene Accession No. O95718
Gene Alias DFNB35, ERR2, ERRb, ESRL2, NR3B2
Gene Symbols ESRRB
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-252 of human ESRRB produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2103
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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