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Invitrogen™ EXD1 Monoclonal Antibody (OTI2G5)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA525350

Product Code. 15944954

  • € 572.00 / 100µL

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Description

Description

EXD1 Monoclonal Antibody for Western Blot, Flow

EXD1 is an RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

EXD1
Monoclonal
0.6 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8NHP7
EXD1
Full length human recombinant protein of EXD1 produced in HEK293T cell.
100 μL
Primary
Human, Rat, Monkey
Antibody
IgG1
Flow Cytometry, Western Blot
OTI2G5
Unconjugated
EXD1
4932702D22Rik; Exd1; EXDL1; exonuclease 3'-5' domain containing 1; exonuclease 3'-5' domain-containing protein 1; exonuclease 3'-5' domain-containing protein 1; piRNA biogenesis protein EXD1; exonuclease 3'-5' domain-like 1; exonuclease 3'-5' domain-like-containing protein 1; Inactive exonuclease EXD1; mExd1; piRNA biogenesis protein EXD1; RGD1561009; Vexonuclease 3'-5' domain-like 1
Mouse
Affinity chromatography
RUO
161829, 311334
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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