missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ F1A alpha Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA519955
This item is not returnable.
View return policy
Description
In Western blot applications, this antibody detects a band at ~70kDa. A suggested positive control is mouse liver tissue lysate. PA5-19955 can be used with blocking peptide PEP-0080.
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1-b. F1Aalpha/FEM1-b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.
Specifications
| F1A alpha | |
| Polyclonal | |
| Unconjugated | |
| FEM1B | |
| DKFZp451E0710; F1aa; F1A-alpha; fem-1 homolog B; fem-1 homolog b (C. elegans); Fem1b; FEM1-beta; FEM-1-like death receptor binding protein; fem-1-like death receptor-binding protein alpha; Fem-1-like in apoptotic pathway protein alpha; feminization 1 homolog b; feminization 1 homolog b (C. elegans); FIAA; Kiaa0396; mKIAA0396; mt-Fem; Protein fem-1 homolog B | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10116, 14155, 315745 | |
| Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P0C6P7, Q9UK73, Q9Z2G0 | |
| FEM1B | |
| A 14 amino acid peptide near the carboxy terminus of human F1A. The immunogen is located within the last 50 amino acids of F1A alpha. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction