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Invitrogen™ FABP3 Polyclonal Antibody

Product Code. 11367683
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Quantity:
100 μg
Unit Size:
100µg
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11367683 100 μg 100µg
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Product Code. 11367683 Supplier Invitrogen™ Supplier No. PA519741

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Beskrivning

Rabbit Polyclonal Antibody

Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with cow and pig based on sequence homology.

Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen FABP3
Applications Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene FABP3
Gene Accession No. P05413
Gene Alias 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3; FABP11; Fabp3; Fabph1; Fabph-1; Fabph4; Fabph-4; fatty acid binding protein 11; Fatty acid binding protein 11 (FABP11); fatty acid binding protein 3; Fatty acid binding protein 3 heart; fatty acid binding protein 3, muscle and heart; Fatty acid binding protein heart; fatty acid binding protein heart 1; fatty acid binding protein heart 4; fatty acid-binding protein 3; Fatty acid-binding protein, heart; heart FABP; heart fatty acid binding protein; Heart type fatty acid binding protein; heart-type fatty acid-binding protein; H-FABP; M FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; M-FABP; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle fatty acid-binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte; O-FABP
Gene Symbols FABP3
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Cardiac FABP.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2170
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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